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On-line deconvolution for protein Circular Dichroism spectra
Featuring NRMSD values, multiple algorithm solutions and the SP175 data set.

Welcome to DichroWeb - the on-line server for protein Circular Dichroism spectra deconvolution. DichroWeb incorporates five popular and effective algorithms to calculate protein secondary structure content. Citing DichroWeb:

 If you use DichroWeb for your analysis you agree to cite the publications detailing the original methods and reference data used, as well as one of the specific DichroWeb papers:

Whitmore, L. and Wallace, B.A. (2008) Biopolymers 89: 392-400.
Whitmore, L. and Wallace, B.A. (2004) Nucleic Acids Research 32: W668-673. (PDF)
DichroWeb News
The recently released SP175, SP175(190) and CRYST175 reference data sets are now available to use.

New book released (contains tips on successful DichroWeb use) Click for Info

Featured Algorithms
Contin-LL
Selcon 3
CDSSTR
VARSLC
K2d

Stats
DichroWeb currently has 2300+ registered users and has performed over 200,000 deconvolutions since 2001.

DichroWeb is produced by Dr. Lee Whitmore, in the lab of Professor Bonnie Wallace
at Birkbeck College, Unversity of London, UK. © 2008
We are supported by the BBSRC.